Yintoni TAGMe
Ihlabathi jikelele likhethekile: ITumor ehambelana neMethylated Epiprobe (TAGMe)
Ekuqinisekisweni kweesampulu zeklinikhi ezingaphezulu kwama-3000, inqanaba le-methylation ye-TAGMe kwizicubu ze-tumor laliphezulu kakhulu kunelo lezicubu eziqhelekileyo.Ke ngoko, i-TAGMe inokusetyenziswa njengemakishi yomhlaza wepan-pan ekubhaqweni komhlaza ohlukeneyo.
Iijini ezinxulumene ne-Histone zine-hypermethylated kumhlaza wemiphunga kwaye i-hypermethylated HIST1H4F inokusebenza njenge-pan-cancer biomarker.
————Uphando lomhlaza, UKUBA:12.7
Deukusebenza tection
Njengomakishi womhlaza wepan, i-TAGMe inento ethile ephezulu kunye novakalelo kuqinisekiso lwesampulu yeklinikhi, enexabiso lereferensi eliyimfuneko kuxilongo lwezonyango lwamathumba.
I-TAGMe inobuntununtunu kwiisampulu zethumba ezahlukeneyo xa ubuchwephesha bungaphezulu kwama-95%,